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053 VITAMIN B6 MAY CUT RISK OF PARKINSON)S DISEASE
Published in Saudi Press Agency on 01 - 08 - 2006

A HIGHER DIETARY INTAKE OF VITAMIN B6 MAY DECREASE THE
RISK OF PARKINSON)S DISEASE A STUDY SUGGESTS ACCORDING TO REUTERS0
AMONG MORE THAN 0005 PEOPLE DUTCH RESEARCHERS FOUND THOSE WHO REPORTED
TAKING IN THE MOST VITAMIN B6 WERE ABOUT HALF AS LIKELY AS THOSE WHO CONSUMED
THE LEAST TO DEVELOP PARKINSON)S DISEASE0
VITAMIN B6 IS ESSENTIAL FOR METABOLISM OF PROTEIN AND PROPER IMMUNE AND
NERVOUS SYSTEM FUNCTION AND IS FOUND IN BOTH MEAT AND VEGETABLES0
THERE IS EVIDENCE THAT HIGH LEVELS OF THE AMINO ACID HOMOCYSTEINE COULD
CAUSE DAMAGE TO BRAIN CELLS0 TO SEE WHETHER HIGHER INTAKE OF FOLATE AND
VITAMINS B6 AND B12 WHICH CAN REDUCE HOMOCYSTEINE LEVELS WOULD ALSO REDUCE
PARKINSON)S RISK RESEARCHERS FOLLOWED 2895 MEN AND WOMEN AGED 55 AND OLDER WHO
WERE FREE OF THE DISEASE AT THE STUDY)S OUTSET0
DURING NEARLY 10 YEARS OF FOLLOW UP 72 PEOPLE DEVELOPED PARKINSON)S DISEASE
DR0 MONIQUE M0 B0 BRETELER OF ERASMUS MEDICAL CENTER IN ROTTERDAM AND
COLLEAGUES REPORT IN THE JOURNAL NEUROLOGY0
THE RESEARCHERS FOUND NO ASSOCIATION BETWEEN CONSUMPTION OF B12 OR FOLIC
ACID AND RISK OF DEVELOPING THE DISEASE0 HOWEVER THE MORE B6 PEOPLE CONSUMED
THE LOWER THEIR RISK0
THOSE IN THE HIGHEST THIRD OF VITAMIN B6 INTAKE WERE 54 PERCENT LESS LIKELY
TO DEVELOP THE DISEASE COMPARED TO THOSE IN THE LOWEST THIRD0 A CLOSER LOOK
SUGGESTED THAT THIS RELATIONSHIP WAS ONLY STATISTICALLY SIGNIFICANT FOR
SMOKERS0
THE FINDINGS SUGGEST THAT THE NUTRIENT COULD LOWER PARKINSON)S DISEASE RISK
NOT BY AFFECTING HOMOCYSTEINE LEVELS BUT BY PROTECTING BRAIN CELLS FROM DAMAGE
CAUSED BY HARMFUL BY-PRODUCTS OF METABOLISM KNOWN AS FREE RADICALS BRETELER AND
HER TEAM PROPOSE0 THEY NOTE THAT SEVERAL STUDIES HAVE SHOWN THAT SMOKING
ACTUALLY CUTS PARKINSON)S RISK POSSIBLY DUE TO BRAIN-CELL-PROTECTING PROPERTIES
OF NICOTINE0
THE STUDY DOESN)T RULE OUT THE POSSIBILITY THAT B12 AND FOLATE COULD ALSO
BE PROTECTIVE THE RESEARCHERS POINT OUT0 TO PROVIDE A MORE DEFINITIVE ANSWER
THEY ADD STUDIES MUST BE CONDUCTED THAT LOOK AT LEVELS OF THE NUTRIENTS IN THE
BLOOD WHICH IS A MORE SENSITIVE INDICATOR OF THEIR EFFECTS0


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