it's that friendly ingredient found in moisturizers and supplement bottles. But did you know there's a powerful form of vitamin E, tucked away in palm oil, that scientists across the globe have been studying for its anti-inflammatory and antioxidant properties? Meet tocotrienols, a lesser-known form of vitamin E that research from around the world has shown can support brain and heart health and liver function. Vitamin E comes in eight forms, but only two families matter most: tocopherols (the kind you will usually see in supplements) and tocotrienols. They may sound similar, but their effects can be dramatically different. Tocotrienols are up to 40-60 timesmore powerful as antioxidants compared to tocopherols and thanks to their unique molecular shape, tocotrienols are able to travel more quickly and deeply into cell membranes, enabling them to neutralize harmful free radicals more efficiently. Palm oil is especially rich in tocotrienols. The distribution of vitamin E in palm oil is 30% tocopherols and 70% tocotrienols. In contrast, other commonly used dietary vegetable oils, including corn, olive, peanut, sesame, soybean, and sunflower, contain tocopherols exclusively. This explains some of palm oil's health benefits, from neuroprotection against Alzheimer's to supporting cardiovascular health and even exhibiting anti-cancer properties. Tocotrienols act as scavenger molecules, neutralizing harmful free radicals that damage cells5. The natural tocotrienols and beta-carotene6 compounds found in palm oil have been linked to improved cardiovascular health and reducing the risk of age-related neurodegenerative diseases. By incorporating palm oil into a balanced diet, positive strides can be made towards supporting heart health. Leading nutrition experts are taking notice of this established research. Dr. Barrie Tan, a trailblazer and the world's foremost expert on vitamin E, has been researching tocotrienols since the 1990s. His work helped identify sources of this compound in palm oil, rice bran, and annatto seeds. He believes tocotrienols are one of the most exciting discoveries in nutrition science today, especially for their effects in fatty organs like the brain and liver. Closer to home, Dr. Eman Gamal, a Clinical Nutrition Specialist practicing in Riyadh, shares this perspective: "Tocotrienols are an exciting area of nutritional science, especially given their potential antioxidant and anti-inflammatory properties. Research has linked vitamin E forms like tocotrienols to better heart health, brain function, and protection of liver cells. These compounds also play a role in supporting skin health and may help slow aspects of the aging process. Including natural sources of vitamin E as part of a balanced diet is one way to support overall wellness." Scientific reviews have documented tocotrienols' role in reducing inflammation, an underlying factor in many chronic conditions. A 2022 study published in the Journal of Functional Foods, examined how tocotrienols interact with inflammation pathways. The researchers found that tocotrienols significantly reduced markers of inflammation in preclinical studies. Another comprehensive review, published by researchers in Oxidative Medicine and Cellular Longevity, documented tocotrienols' benefits for brain function, cardiovascular health, and even skin aging. Importantly, they noted that tocotrienols showed no recognized adverse effects in the clinical studies they reviewed, making them a safe and promising area for continued research. A particularly revealing Swedish study conducted by the Karolinska Institute4 found that individuals with Alzheimer's disease or mild cognitive impairment had lower levels of tocotrienols and tocopherols in their blood compared to healthy individuals, establishing a clear link between vitamin E forms and cognitive health. The consistent findings demonstrate that tocotrienols deliver measurable health benefits. With documented effects on inflammation, brain health, and cardiovascular wellness, and with no known side effects, tocotrienols have earned their place in serious nutritional research. As research continues to build on these established benefits, it's remarkable to consider how compounds in everyday ingredients can contribute to better health. The growing body of evidence shows that sometimes the most powerful nutrients are hiding in plain sight, quietly supporting our wellbeing through ingredients we use every day. The science is clear: these lesser-known nutrients have been delivering real benefits all along.
